2- Mechanism of virus specificity and host range

2- Mechanism of virus specificity and host range

Like most pathogens, densoviruses can be specialists (one virus infects one host species) or generalists (one virus can infect several species) and is a correlation between the host range and the host phylogeny.

Our research focuses on i) the virus determinants of specificity (capsid and genome) using an “a priori” approach based on motif-candidate on the capsid and we are developing a high throughput approach to decipher the virus determinants.  ii) the mechanim of virus adaptation to new hosts using experimental evolution in different host species.

Modification date : 17 July 2023 | Publication date : 14 March 2022 | Redactor : A-S Gosselin-Grenet, I. Seninet